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Inherited enzyme deficiencies and immunodeficiency: Adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) deficiencies

✍ Scribed by Rochelle Hirschhorn


Book ID
118374637
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
736 KB
Volume
40
Category
Article
ISSN
1090-2341

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## Abstract Cultured skin fibroblasts from a patient with T‐cell immune deficiency and an absence of purine nucleoside phosphorylase activity in red cells were assayed for their capacity to metabolize inosine and guanosine. The cultured fibroblasts were lacking activity of nucleoside phosphorylase