Inherited canine giant axonal neuropathy
โ Scribed by Dr. Ian D. Duncan; Dr. Ian R. Griffiths; Dr. Stewart Carmichael; Dr. Susan Henderson
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 488 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
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## Abstract Magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), and MR spectroscopy (MRS) data were obtained in a patient with giant axonal neuropathy (GAN) and compared to a control group. Fractional anisotropy (FA) and apparent coefficient diffusion (ADC) data were obtained from spe
Giant axonal neuropathy (GAN), a progressive childhood disorder of intermediate filaments (IF), is characterized by a peripheral neuropathy and central nervous system involvement. Twenty-eight cases have been reported while several pathogenic hypotheses have been proposed. Sural nerve biopsy of a 10