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Inheritable Molecular Variants of Moderate and Mild Hemophilia A

✍ Scribed by Ljung, Rolf ;Holmberg, Lars ;Nilsson, Inga Marie


Book ID
114692657
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
412 KB
Volume
209
Category
Article
ISSN
0001-6101

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## Communicated by Arupa Ganguly The amount of residual F8 (FVIII:C) determines the clinical severity of hemophilia A. Recently, we showed that the mutation detection rate in severely affected male patients (FVIII:Co1% of normal) is virtually 100% when testing for the common intron 22-/intron 1-in