Spectrum of molecular defects and mutati
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Nadja Bogdanova; Arseni Markoff; Roswith Eisert; Cornelia Wermes; Hartmut Pollma
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Article
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2007
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John Wiley and Sons
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English
β 355 KB
## Communicated by Arupa Ganguly The amount of residual F8 (FVIII:C) determines the clinical severity of hemophilia A. Recently, we showed that the mutation detection rate in severely affected male patients (FVIII:Co1% of normal) is virtually 100% when testing for the common intron 22-/intron 1-in