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Inherently chiral calix[4]crown ethers

✍ Scribed by Sebatiano Pappalardo; Melchiorre F. Parisi


Book ID
103406642
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
290 KB
Volume
37
Category
Article
ISSN
0040-4039

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The first example of the resolution of inherently chiral calix[8]arenes, 1,4-2,5-calix[8]bis-crown-4 1 and its methyl derivatives 2,-4, has been achieved using enantioselective HPLC methods. The enantiomeric nature of isolated (+)-1 and (-)-1 was confirmed by CD spectra, specific optical rotation an