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Infrared Study of the Stability and Folding Kinetics of a 15-Residue β -Hairpin

✍ Scribed by Xu, Yao; Oyola, Rolando; Gai, Feng


Book ID
121867837
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
127 KB
Volume
125
Category
Article
ISSN
0002-7863

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Folding of beta-hairpin structures of synthetic peptides has been simulated using the molecular dynamics method with a solvent-referenced potential. Two similar sequences, Ac-MQIFVKS(D)PGKTITLKV-NH(2) and Ac-MQIFVKS(L)PGKTITLKV-NH(2), derived from the N-terminal beta-hairpin of ubiquitin, were used