Infrared radiation suppresses ultraviolet B-induced sunburn-cell formation

✍ Scribed by K. Danno; T. Horio; S. Imamura

• Book ID: 104746608
• Publisher: Springer-Verlag
• Year: 1992
• Tongue: English
• Weight: 278 KB
• Volume: 284
• Category: Article
• ISSN: 0340-3696
• DOI: 10.1007/bf00373376

✦ Synopsis

Sunburn cell (SC) formation, a quantifiable measure of epidermal cell injury induced in mouse ear skin by ultraviolet-B (UVB) radiation (290-320nm), was significantly decreased by pre-exposure to infrared radiation (IR), which elevated the surface temperature of ear lobes to 37-42 ~ An autoradiographic study demonstrated that the basal cell labelling indices were significantly reduced in a surface temperature-dependent manner by pre-exposure to IR. Taken together with our previous findings that SC formation depends upon the ratio of cycling to non-cycling cells, the present findings suggest that IR retards the cell cycle and, as a result, decreases SC formation. SC counts were not altered by post-UVB exposure to IR. The effect of IR or the IR-induced increase in surface temperature should be considered when studying cutaneous damage by UVB and sunlight.