Infrared Dichroism of Isotope-edited α-Helices and β-Sheets
✍ Scribed by Derek Marsh
- Book ID
- 116661252
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 730 KB
- Volume
- 338
- Category
- Article
- ISSN
- 0022-2836
No coin nor oath required. For personal study only.
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## Abstract Vibrational CD (VCD) of amides A, I, and II vibrations of a variety of polypeptide films have been measured. VCD of films of α‐helical and β‐sheet structures are compared in the three regions. Reproducible spectra could only be obtained for thin films free of orientation dependence. The
## Abstract Deuterium exchange was monitored by electrospray ionization mass spectrometry (ESI‐MS) to study the slowly exchanging (hydrogen bonded) peptide hydrogens of several α‐helical peptides and β‐sheet proteins. Polypeptides were synthetically engineered to have mainly disordered, α‐helical,