Genetic events associated with arsenic-i
โ
Hua Chen; Jie Liu; Bruce A. Merrick; Michael P. Waalkes
๐
Article
๐
2001
๐
John Wiley and Sons
๐
English
โ 209 KB
Arsenic is a human carcinogen. Our recent work showed that chronic ( b 18 wk), low-level (125ยฑ500 nM) arsenite exposure induces malignant transformation in normal rat liver cell line TRL1215. In these arsenic-transformed cells, the cellular S-adenosylmethionine pool was depleted from arsenic metabol