Influx of nonactivated T lymphocytes into the cerebrospinal fluid during relapse of multiple sclerosis

✍ Scribed by Dr Olli Oksaranta; Sinikka Tarvonen; Jorma Ilonen; Kari Poikonen; Mauri Reunanen; Martin Panelius; Reijo Salonen

• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 399 KB
• Volume: 38
• Category: Article
• ISSN: 0364-5134
• DOI: 10.1002/ana.410380320

✦ Synopsis

Cl6, 173. It may also signify the presence in western countries, but not in Nigeria, of other genetic or environmental factors that act in concert with the €4 allele to produce the association between €4 and AD. We also recognize that ancestral origin cannot always be defined with precision in the African-American population. It has been estimated that, for example, European admixture within African Americans is considerable, approximately 25% C18).

In conclusion, in a study involving small numbers of subjects, no association between the presence of the a4 allele and AD or dementia was seen in a community-based population of elderly Nigerian subjects. This result is in marked contrast to the results of our previously reported study with African-American subjects {GI. Our results with Nigerian subjects warrant further study with large samples.