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Influenza A and Sendai Viruses Induce Differential Chemokine Gene Expression and Transcription Factor Activation in Human Macrophages

✍ Scribed by Sampsa Matikainen; Jaana Pirhonen; Minja Miettinen; Anne Lehtonen; Carola Govenius-Vintola; Timo Sareneva; Ilkka Julkunen


Book ID
112273201
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
469 KB
Volume
276
Category
Article
ISSN
0042-6822

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Bacterial lipopolysaccharide (LPS) has been shown to induce a wide variety of proinflammatory cytokines and chemokines. An initial challenge with minute amounts of LPS causes tolerance to later LPS effects which is characterized by a much lower or abrogated release of pro-inflammatory cytokines. To