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Influences of Organic Cation Transporter Polymorphisms on the Population Pharmacokinetics of Metformin in Healthy Subjects

โœ Scribed by Hwa Yoon, Hea-Young Cho, Hee-Doo Yoo, Se-Mi Kim, Yong-Bok Lee


Book ID
120957462
Publisher
American Association of Pharmaceutical Scientists
Year
2013
Tongue
English
Weight
337 KB
Volume
15
Category
Article
ISSN
1550-7416

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Functional characterization of human org
โœ Yuki Kawasaki; Yukio Kato; Yoshimichi Sai; Akira Tsuji ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 139 KB ๐Ÿ‘ 1 views

The organic cation transporter OCTN1 (SLC22A4) is expressed ubiquitously, with strong expression in kidney, trachea, bone marrow, and fetal liver, and it mediates transport of organic cations in a pH-dependent manner. Recent studies have identified single nucleotide polymorphisms (SNPs) of OCTN1 in