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Influence of viscous incubation media on the resistance to diffusion of the intestinal unstirred water layer in vitro

✍ Scribed by Ian T. Johnson; Jennifer M. Gee


Book ID
104819720
Publisher
Springer
Year
1982
Tongue
English
Weight
532 KB
Volume
393
Category
Article
ISSN
0031-6768

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The presence of an aqueous diffusion layer or 'unstirred' water layer adjacent to the intestinal membrane has long been regarded as a potential barrier for intestinal absorption of compounds. Theoretical analyses were performed in the present study to quantitatively determine the effect of this laye