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Influence of various antimicrobial agents on the intestinal flora in an intestinal MRSA-carrying rat model

✍ Scribed by Masahiro Takahata; Yoko Sugiura; Satoshi Ameyama; Akira Yotsuji; Junichi Mitsuyama; Yoshinobu Sumiyama; Shinya Kusachi


Publisher
Springer
Year
2004
Tongue
English
Weight
266 KB
Volume
10
Category
Article
ISSN
1341-321X

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The oral bioavailability of tributylmethyl ammonium (TBuMA), an organic cation (OC), exhibited a dose-dependency (i.e., 17, 27, and 35% at doses of 0.4, 4, or 12 micromol/kg, respectively) in the rat. Relevant mechanisms were investigated in the present study by estimating the mucosal to serosal (m-