Influence of Trypan Blue on Resorption of Rat Embryos
β Scribed by SMITH, W. N. ADAMS
- Book ID
- 109631741
- Publisher
- Nature Publishing Group
- Year
- 1963
- Tongue
- English
- Weight
- 257 KB
- Volume
- 200
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/200699a0
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## Abstract Tenβday chick embryos (1) received yolk sac injections of 0.1 ml of 1.5% trypan blue in sterile saline, (2) received 0.1 ml of sterile saline or (3) were handled and returned to the incubator and examined five hours later. Trypan blue treated embryos exhibited decreased survival rate an
Treatment of chick embryos early in development with the teratogen, trypan blue, results in a high incidence of rumplessness at later developmental stages. Experiments were conducted to discover the causative events between dye administration and rumplessness. Initially, 167 two-day embryos were tre