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Influence of tilorone hydrochloride on the secondary structure and template activity of DNA

✍ Scribed by P. Chandra; F. Zunino; A. Zaccara; A. Wacker; A. Götz


Book ID
115902802
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
297 KB
Volume
23
Category
Article
ISSN
0014-5793

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The interaction between 4'-6-Diamidino-2-Phenylindole-hydrochloride (DAPI) and a variety of DNAs and synthetic polydeoxynucleotides was investigated in order to delineate the nucleic acid structural features necessary for binding. The spectra of DAPI-DNA complexes, measured at various DAPI:DNA molar