✦ LIBER ✦

Influence of the time of phenobarbital treatment on liver tumor development in initiated B6C3F1 mice

✍ Scribed by Christopher M. Weghorst; Michael A. Pereira; James E. Klaunig

Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 57 KB
Volume: 47
Category: Article
ISSN: 0300-483X
DOI: 10.1016/0300-483x(87)90177-6

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Comparison of effect of tumor promoter t

Comparison of effect of tumor promoter treatments on DNA methylation status and gene expression in B6C3F1 and C57BL/6 mouse liver and in B6C3F1 mouse liver tumors

✍ Jennifer L. Counts; R. Michael McClain; Jay I. Goodman 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 263 KB 👁 2 views

The effects of different liver tumor-promoting treatments (i.e., a choline-devoid, methionine-deficient (CMD) diet, phenobarbital (PB), or both) on Ha-ras and raf methylation status and expression were determined in mouse strains with different susceptibilities to liver tumor formation: the relative

Alterations in the methylation status an

Alterations in the methylation status and expression of the raf oncogene in phenobarbital-induced and spontaneous B6C3F1 mouse liver tumors

✍ Jean S. Ray; Margaret L. Harbison; R. Michael McClain; Jay I. Goodman 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 974 KB

## Abstract The liver tumor‐prone B6C3F1 mouse (C57BL/6 ♂ × C3H/He♀), in conjunction with the more susceptible C3H/He paternal strain and the resistant C57BL/6 maternal strain, is an excellent model for studying the mechanisms involved in carcinogenesis. The study reported here indicated that the B

Differential effects of dihalogenated an

Differential effects of dihalogenated and trihalogenated acetates in the liver of B6C3F1 mice

✍ J. Kato-Weinstein; A. J. Stauber; G. A. Orner; B. D. Thrall; R. J. Bull 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 744 KB

## Abstract Haloacetates are produced in the chlorination of drinking water in the range 10–100 μg l^−1^. As bromide concentrations increase, brominated haloacetates such as bromodichloroacetate (BDCA), bromochloroacetate (BCA) and dibromoacetate (DBA) appear at higher concentrations than the chlor

Haloacetate-induced oxidative damage to

Haloacetate-induced oxidative damage to DNA in the liver of male B6C3F1 mice

✍ Jeff M. Parrish; E.W. Austin; D.K. Stevens; D.H. Kinder; R.J. Bull 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 788 KB

Effect of peroxisome proliferators on th

Effect of peroxisome proliferators on the methylation and protein level of the c-myc protooncogene in B6C3F1 mice liver

✍ Rongrong Ge; Lianhui Tao; Paula M. Kramer; Michael L. Cunningham; Michael A. Per 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB

## Abstract Peroxisome proliferators in general are nongenotoxic mouse liver carcinogens for which DNA hypomethylation and altered gene expression are proposed mechanisms. Therefore, the peroxisome proliferators 2,4‐dichlorophenoxyacetic acid (2,4‐D), dibutyl phthalate (DBP), gemfibrozil, and Wy‐14

Effect of trichloroethylene on DNA methy

Effect of trichloroethylene on DNA methylation and expression of early-intermediate protooncogenes in the liver of B6C3F1 mice

✍ Lianhui Tao; Rongrong Ge; Mi Xie; Paula M. Kramer; Michael A. Pereira 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 3 views

Trichloroethylene (TCE) is a multimedia environmental pollution that is carcinogenic in mouse liver. The ability of TCE to modulate DNA methylation and the expression of immediate-early protooncogenes was evaluated. Female B6C3F1 mice were administered 1000 mg/kg TCE by gavage 5 days/week and killed