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Influence of the structure of substituted benzodiazepines on their pharmacokinetic properties

✍ Scribed by A. G. Artemenko; V. E. Kuz’min; E. N. Muratov; P. G. Polishchuk; I. Yu. Borisyuk; N. Ya. Golovenko


Book ID
106492077
Publisher
Springer
Year
2009
Tongue
English
Weight
231 KB
Volume
43
Category
Article
ISSN
0091-150X

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The purpose of this study was to investigate the effect of the total degree of substitution (TDS) on the colligative properties of substituted cyclodextrins (CDs; i.e., b-and g-cyclodextrins substituted with sulfobutylether or hydroxypropyl groups) in solution. The osmotic pressure (OP) of aqueous C