Influence of the route of administration on the pharmacokinetics of pirprofen enantiomers in the rat
โ Scribed by Dion R. Brocks; William T.C. Liang; Dr. Fakhreddin Jamali
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 437 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Flurbiprofen is a chiral 2-arylpropionate used clinically as a racemate. Previously a significant pharmacokinetic interaction between the enantiomers of flurbiprofen has been reported in both rats and humans. The possible mechanism for this interaction was believed to involve competitive protein bin
Verapamil is a chiral calcium channel blocking drug which is useful clinically as the racemate in treating hypertension and arrhythmia. The published pharmacokinetic data for verapamil enantiomers in the rat model are limited. Utilizing a stereospeciยฎc highperformance liquid chromatographic (HPLC) a