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Influence of the Buffering Capacity of the Medium on the Dissolution of Drug-Excipient Mixtures

โœ Scribed by Ramtoola, Z.; Corrigan, O. I.

Book ID
120822867
Publisher
Informa plc
Year
1989
Tongue
English
Weight
574 KB
Volume
15
Category
Article
ISSN
0363-9045

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To gain a deeper understanding of the behavior of carbamazepine (CBZ) and CBZ dihydrate (DH) compacts during in vitro dissolution tests various factors were investigated: hydrate formation of CBZ, crystal morphology, surface area, and excipient influence. Dissolution tests were performed in three di