Influence of the Arene Ligand and the Leaving Group on the Anticancer Activity of (Thio)maltol Ruthenium(II)?(η 6 -Arene) Complexes
✍ Scribed by Hanif, Muhammad; Schaaf, Patricia; Kandioller, Wolfgang; Hejl, Michaela; Jakupec, Michael A.; Roller, Alexander; Keppler, Bernhard K.; Hartinger, Christian G.
- Book ID
- 120375926
- Publisher
- Commonwealth Scientific and Industrial Research Organisation Publishing
- Year
- 2010
- Tongue
- English
- Weight
- 348 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0004-9425
- DOI
- 10.1071/CH10232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Piano stool ruthenium complexes of the composition [Ru(II)(η^6^‐arene)(en)Cl]^+/2+^ (en = ethylenediamine) represent an emerging class of cisplatin‐analogue anticancer drug candidates. In this study, we use computational quantum chemistry to characterize the structure, stability and rea
## Abstract Organometallic ruthenium–arene compounds bearing a maltol ligand have been shown to be nearly inactive in in vitro anticancer assays, presumably due to the formation of dimeric Ru^II^ species in aqueous solutions. In an attempt to stabilize such complexes, [Ru(η^6^‐__p__‐cymene)(XY)Cl]