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Influence of Temperature on Solvent-Mediated Anhydrate-to-Hydrate Transformation Kinetics

✍ Scribed by Haiyan Qu; Tommy Munk; Claus Cornett; Jian X. Wu; Johan P. Bøtker; Lars P. Christensen; Jukka Rantanen; Fang Tian

Book ID
106494092
Publisher
Springer US
Year
2010
Tongue
English
Weight
296 KB
Volume
28
Category
Article
ISSN
0724-8741

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Solvent-mediated polymorphic transformation is an ef®cient technique to obtain the most stable polymorph. The rate of solvent-mediated polymorphic transformation of sulfamerazine at 248C in various solvents and solvent mixtures is controlled by the nucleation rate of the more stable Form II. The tra