## Abstract Preparations have been made of acidβsoluble collagens whose telopeptides have suffered different levels of proteolytic attack. The collagens with more intact telopeptides form fibrils more rapidly than those with degraded telopeptides. In addition, we have shown that a high molecular we
Influence of telopeptide on the morphology and physicomechanical properties of reconstituted collagens
β Scribed by James C. W. Chien; E. P. Chang
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1973
- Tongue
- English
- Weight
- 573 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0006-3525
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β¦ Synopsis
Abstract
The morphology and physicomechanical properties of two types of collagen membranes, one of which does not have telopeptides, were compared with smallβangle light scattering, rheoβoptical, dynamic mechanical, and dynamic rheoβoptical techniques. The presence of telopeptides in native collagen allows the formation of larger rodβlike superstructures; it renders the membrane more resistant to irreversible deformation yet more responsive to dynamic mechanical perturbation. Telopeptides are also responsible for relaxation at room temperature, and impart more linearly elastic properties to the material as compared to membranes derived from enzymeβtreated collagens.
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