## Background: Telomerase is a ribonucleoprotein enzyme that extends telomere specific repeats on the ends of chromosomes. telomerase activity has been detected frequently in various types of human tumors and has been associated with cell immortality and oncogenesis. human telomerase reverse transc
β¦ LIBER β¦
Influence of telomerase activity on bone and soft tissue tumors
β Scribed by Norifumi Umehara; Toshifumi Ozaki; Shinsuke Sugihara; Toshiyuki Kunisada; Yuki Morimoto; Akira Kawai; Keiichiro Nishida; Aki Yoshida; Takuro Murakami; Hajime Inoue
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 223 KB
- Volume
- 130
- Category
- Article
- ISSN
- 1432-1335
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## Abstract Samples from 48 benign and 102 malignant bone and softβtissue tumors were analyzed cytogenetically and by DNA flow cytometry. Clonal chromosome abnormalities were found in 82 tumors and normal karyotypes in 68; 61 tumors were DNAβnonβdiploid and 89 were diploid. The cytogenetically abno