Direct measurements of the pull-off (adhesion) forces between pharmaceutical particles (beclomethasone dipropionate, a peptide-type material, and lactose) with irregular geometry and rough polymeric surfaces (series of polypropylene coatings, polycarbonate, and acrylonitrile-butadiene-styrene) were
Influence of Surface Roughness on the Pull-Off Force in Atomic Force Microscopy
โ Scribed by Jang, J.; Sung, J.; Schatz, G.C.
- Book ID
- 121247109
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 447 KB
- Volume
- 111
- Category
- Article
- ISSN
- 1932-7447
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Adhesion force distributions of silica spheres (5 and 20 mm) and salmeterol xinafoate (4 mm) particles with inhalation grade lactose surfaces and spin coated lactose films were determined by atomic force microscopy (AFM) to investigate the influence of surface roughness on the force distributions. T