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Influence of substance P on the behavioral changes induced by haloperidol in rats

✍ Scribed by Jolicoeur, Francois B.; Rondeau, Daniel B.; Belanger, Ferdinand; Fouriezos, George; Barbeau, André

Book ID
122765847
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
478 KB
Volume
1
Category
Article
ISSN
0196-9781

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We investigated the effects of a schizophrenomimetic drug, phencyclidine (PCP), on substance P (SP) contents in the discrete rat brain areas using an enzyme-immunoassay for SP. The acute intraperitoneal (i.p.) administration of PCP (10 mg/kg), which is a noncompetitive antagonist of the N-methyl-D-a