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Influence of spironolactone pretreatment on pharmacokinetics and metabolism of digitoxin in rats

✍ Scribed by H. -F. Vöhringer; L. Weller; N. Rietbrock

Book ID: 112351811
Publisher: Springer-Verlag
Year: 1975
Tongue: English
Weight: 570 KB
Volume: 287
Category: Article
ISSN: 0028-1298
DOI: 10.1007/bf00510445

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Preparation of (f)-Laudaniae (1V) from I-Sodium borohydride (0.1 9.) was added in portjons to a solution of I (0.1 8.) in ethanol and the mixture was stirred at room temperature for 3 hr. Methanol was added and after 30 min. the reaction mixture was evaporated to dryness. The residue was dissolved i