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Influence of scheduling, dose, and volume of administration of a perfluorochemical emulsion on tumor response to radiation therapy

โœ Scribed by Beverly A. Teicher; Terence S. Herman; Steven M. Jones


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
845 KB
Volume
19
Category
Article
ISSN
0360-3016

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## Abstract Nitrosoheptamethyleneimine (NHMI) was tested for carcinogenicity in Fischerโ€344 and Spragueโ€Dawley rats by intragastric administration and subcutaneous injection. Cumulative doses ranged from 5.5 to 1,200 mg/kg, and dosage schedules ranged from 40 serial administrations to one single in