Influence of sampling time on assessment of potential doubling time
✍ Scribed by Morten Høyer; Søren M. Bentzen; Lisbeth N. Salling; Jens Overgaard
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 714 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The in vivo infusion of Bromodeoxyuridine (BrdUrd), followed by delayed biopsy and bivariate DNA-BrdUrd flow cytometry, allows the potential doubling time (T pot ) of human tumors to be estimated. According to Steel, the mathematical definition of T pot is T pot ؍ ln 2/K p , where K p is the rate
In colorectal cancer, tumoral kinetic parameters could influence the therapeutic strategy. The aim of this study was to test the validity of a preoperative assessment of tumoral kinetics on biopsies obtained from endoscopic sampling. After infusion of 250 mg of bromodeoxyuridine (BrdUrd), tumor samp