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Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes

✍ Scribed by H. Glaeser; S. Drescher; M. Eichelbaum; M. F. Fromm

Book ID
108640261
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
144 KB
Volume
59
Category
Article
ISSN
0306-5251

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The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating