Influence of purified apoprotein E on platelet activation induced by serotonin
✍ Scribed by Pfennig, Olaf; Zhao, Bin; Dierichs, Rolf
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 845 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
✦ Synopsis
Serotonin induces platelet activation. Purified apoprotein E of 300 pg/ml prevented morphological alterations of blood platelets stimulated with serotonin (5 pM). Lower concentrated apoprotein E showed no such clear effects. These findings suggest that apoprotein E may liter atherosclerosis by suppressing agonist-induced platelet activation.
📜 SIMILAR VOLUMES
## Abstract Oxidized cellulose is an effective haemostat that works naturally to aid in blood coagulation. The mechanism of its action is not very well understood. Little effect on blood coagulation, but a pronounce decrease in platelet count has been reported upon the addition of the oxidized cell
## Abstract Poly(__N__,__N__‐dimethylacrylamide) (PDMA) brushes are successfully grown from unplasticized poly(vinyl chloride) (uPVC) by well‐controlled surface‐initiated atom transfer radical polymerization (SI‐ATRP). Molecular weights of the grafted PDMA brushes vary from ≈ 35 000 to 2 170 000 Da
## Abstract ## Objective Thrombosis and thrombocytopenia are features of the antiphospholipid syndrome (APS), suggesting that antiphospholipid antibodies (aPL) may bind platelets, causing activation and aggregation of platelets and thrombosis. The intracellular events involved in aPL‐mediated plat