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Influence of pudendal nerve blockade on stress relaxation in the female urethra

✍ Scribed by Peter Thind; Per Bagi; Christoffer Mieszczak; Gunnar Lose


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
347 KB
Volume
15
Category
Article
ISSN
0733-2467

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✦ Synopsis


The urethral pressure decay following a sudden and sustained dilatation corresponds to stress relaxation. Urethral stress relaxation can be described by the equation PI = Pequ + P,eCfiTa + P,e where P, is the pressure at time t, Pequ is the equilibrium pressure after dilatation, P, and P, are pressure decay, and 7, and 7, are time constants. The time constants have previously proved independent of the way the dilatation is performed. The urethral stress relaxation obtained in 10 healthy women before and after pudendal nerve blockade was analysed by the mathematical model and the pressure parameters and time constants determined. The fast time constant, 7,' was reduced by the nerve blockade, whereas 7, was unaffected, however, both P, and P, were reduced. No single stress relaxation parameter can therefore be related to the muscle or the connective tissue components. The method may prove useful in the further evaluation of the closure function of the urethra with special reference to the pathophysiology of stress urinary incontinence.