𝔖 Bobbio Scriptorium
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INFLUENCE OF PLASMA LEVELS AND METABOLISM ON PHARMACOLOGICAL ACTIVITY: PENTAZOCINE

✍ Scribed by Barry Berkowitz

Book ID
114879551
Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
625 KB
Volume
179
Category
Article
ISSN
0890-6564

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✍ Leonid M. Berezhkovskiy πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 204 KB πŸ‘ 1 views

The effect of variable protein binding (taken as independent parameter) on pharmacological activity of drugs is considered in terms of the exposure or the steady state concentration of unbound drug at targeted tissue. Based on the application of the parallel tube or dispersion models it is shown tha