Influence of protein conformation and ad
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Amber L. Clausi; Andrea Morin; John F. Carpenter; Theodore W. Randolph
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Article
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2009
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John Wiley and Sons
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English
โ 228 KB
The mechanism(s) of the enhancement of the immune response by addition of aluminum salt adjuvants to parenterally administered protein-based vaccines is still the subject of debate. It has been hypothesized, however, that destabilization of the antigen structure on the surface of the adjuvant may be