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Influence of particle size and antigen binding on effectiveness of aluminum salt adjuvants in a model lysozyme vaccine

โœ Scribed by Amber Clausi; Jessica Cummiskey; Scott Merkley; John F. Carpenter; LaToya Jones Braun; Theodore W. Randolph


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
263 KB
Volume
97
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES


Influence of protein conformation and ad
โœ Amber L. Clausi; Andrea Morin; John F. Carpenter; Theodore W. Randolph ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 228 KB

The mechanism(s) of the enhancement of the immune response by addition of aluminum salt adjuvants to parenterally administered protein-based vaccines is still the subject of debate. It has been hypothesized, however, that destabilization of the antigen structure on the surface of the adjuvant may be