Influence of noise, peak position and spectral similarities on resolvability of diode-array high-performance liquid chromatography by evolutionary factor analysis

On-Line Recognition and Quantitation of

On-Line Recognition and Quantitation of Coeluting Hypoxanthine and Guanine in Reversed-Phase High-Performance Liquid Chromatography of Placental Tissue Extracts: Photodiode-Array Detection and Spectral Analysis of Coeluting Peaks

✍ I. Szabo; M.H. Maguire 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 655 KB

In a reversed-phase HPLC method, optimized for resolution and quantitation of nucleosides and nucleobases in human term placental extracts, guanine coeluted with hypoxanthine. Three numerical techniques that treat spectral data generated by photodiode-array detection to yield indices of peak purity