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Influence of N -Methylation on a Cation−π Interaction Produces a Remarkably Stable β-Hairpin Peptide

✍ Scribed by Hughes, Robert M.; Waters, Marcey L.


Book ID
120168585
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
60 KB
Volume
127
Category
Article
ISSN
0002-7863

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Effects of Chain Length and N-Methylatio
✍ Robert M. Hughes; Matthew L. Benshoff; Marcey L. Waters 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 806 KB

## Abstract The effects of N‐methylation and chain length on a cation–π interaction have been investigated within the context of a β‐hairpin peptide. Significant enhancement of the interaction and structural stabilization of the hairpin have been observed upon Lys methylation. Thermodynamic analysi