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Influence of methylation of the histidine ring of [Sar1]angiotensin II on conformation and biological activity

✍ Scribed by MOORE, GRAHAM J ;GOGHARI, MAHESH H ;FRANKLIN, KEVIN J


Book ID
115099465
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
423 KB
Volume
42
Category
Article
ISSN
0367-8377

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Biological activity of the novel cyclic
✍ Demetrios V. Vlahakos; John M. Matsoukas; Juris Ancans; Graham J. Moore; Efstath πŸ“‚ Article πŸ“… 1996 πŸ› Springer Netherlands 🌐 English βš– 293 KB

This study was undertaken to investigate the biological activity of the cyclic amide-linked analogue of angiotensin II (ANG II), [Sar~,Lys3,GIuS]ANG II, in both ex vivo and in vivo experiments. This constrained analogue was designed on the basis of a recently suggested conformational model for ANG I