Influence of mechanical stress on the growth of Rhizopus nigricans in stirred bioreactors

✍ Scribed by Prof. Dr.-Ing. Matthias Reuß

• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 798 KB
• Volume: 11
• Category: Article
• ISSN: 0930-7516
• DOI: 10.1002/ceat.270110124

✦ Synopsis

Influence of Mechanical Stress on the Growth of Rhizupus nigricans in

Stirred Bioreactors *

Matthias ReuB**

This investigation was undertaken in order to examine the factors affecting mechanical damage to micro-organisms in stirred bioreactors. Growth of the mould Rhizopus nigricans was studied in stirred bioreactors at different geometrical and operating parameters. Since experimental results cannot be described by conventional key parameters, a new concept has been suggested. It is based on the analogy to processes of mechanical disintegration. It is shown that the same key parameter, i.e. the ratio of power input to flow rate, can be used for a satisfactory correlation of experimental data on mechanical damage to micro-organisms, which is an important step in the recovery of intracellular products in biotechnology .

* Paper presented at the "Jahrestreffen der Verfahrensingenieure" ,