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Influence of lipid peroxidation on the nicotinic acetylcholine receptors in PC12 cells

โœ Scribed by Zhi-Zhong Guan; Xiao Zhang; Agneta Nordberg

Book ID
117470790
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
193 KB
Volume
286
Category
Article
ISSN
0304-3940

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## Abstract The mechanisms involved in the loss of nicotinic acetylcholine receptors (nAChRs), seen in brains of patients with Alzheimer's disease (AD) and in cultured cells treated by ฮฒโ€amyloid peptides (Aฮฒs), remain elusive. We give results to show that lipid peroxidation induced directly by Aฮฒ m