𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of ligand binding to human cytochrome P-450 1A2: conformational activation and stabilization by α-naphthoflavone

✍ Scribed by Uhn S Cho; Hyung J Ahn; Eun Y Park; Mi S Dong; Kyung H Kim


Book ID
114148987
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
369 KB
Volume
1546
Category
Article
ISSN
0167-4838

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Tight-binding inhibition by α-naphthofla
✍ Uhn Soo Cho; Eun Young Park; Mi Sook Dong; Bum Seok Park; Keehyuk Kim; Kyung Hyu 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 429 KB

Human cytochrome P450 (P450) enzymes exhibit remarkable diversity in their substrate specificities, participating in oxidation reactions of a wide range of xenobiotic drugs. Previously, we reported that alpha-naphthoflavone (ANF) is bound to the recombinant P450 1A2 tightly and stabilizes an overall