Influence of leptin in the development of hepatic fibrosis produced in mice by Schistosoma mansoni infection and by chronic carbon tetrachloride administration

Hepatic fibrosis in rats produced by car

Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: Observations suggesting immunoassays of serum for the 75 fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal propeptide of type III procollagen

✍ Leena Ala-Kokko; Volkmar Günzler; Jan B. Hoek; Emanuel Rubin; Darwin J. Prockop 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 567 KB

Liver fibrosis was induced in rats both with carbon tetrachloride and dimethylnitrosamine. Assays were performed on steady-state levels of messenger RNAs in the liver for several collagens and basement membrane components. The results indicated marked increases in the steady-state levels of messenge