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Influence of isotonic agents on the stability of thimerosal in ophthalmic formulations

โœ Scribed by M. J. Reader

Book ID
102406580
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
253 KB
Volume
73
Category
Article
ISSN
0022-3549

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The effect of bulking agents on the chemical stability of acid-sensitive compounds in freeze-dried formulations: Sucrose inversion study
โœ Enxian Lu; Susan Ewing; Larry Gatlin; Raj Suryanarayanan; Evgenyi Shalaev ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 172 KB ๐Ÿ‘ 1 views

The goal of the study was to evaluate the impact of amorphous bulking agents on the chemical stability of freeze-dried materials. Polyvinylpyrrolidone and dextran of different molecular weights and lactose were used as bulking agents, and sucrose was used as an example of an acid-sensitive compound.