✦ LIBER ✦
Influence of Insulin and Glucagon on the Cholesterol Synthesis in Rat Liver in vivo. Evidence against a Rate Limiting Function of the HMG-Coenzyme A Reductase
✍ Scribed by Oswald; Verena Wiss
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- German
- Weight
- 133 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Physiological doses of insulin and glucagon in the range of 0.5–2.5 m unit and 0.05‐2 μg respectively per 100 g body weight stimulate first and inhibit afterwards the cholesterol synthesis from labeled acetate in rat liver in vivo. It could be shown that these effects are not caused by a regulating influence of the HMG‐coenzyme A reductase.