Influence of instrumental parameters and sample preparation on mass-analysed ion kinetic energy spectra with fast atom bombardment exemplified with the oxonium ion of peracetylated ribopyranose
✍ Scribed by Leonore Blok-Tip; Wigger Heerma; Johan Haverkamp
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 358 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1076-5174
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✦ Synopsis
When mass-analysed ion kinetic energy (MIKE) spectra are required to discriminate between isomeric ions formed under conditons of fast atom bombardment (FAB) in the ion source, severe interference may be observed. The interfering peaks in MIKE spectra obtained with a reversed-geometry instrument can arise from different sources. Moreover, the intensity distribution of the true ions from the selected precursor ion may depend strongly on the instrument being used. This means that the FAB-MIKE or collisionally induced dissociation (CID) spectrum is not an absolute characteristic of a particular ion. The [ M + H -HOAc] + ion in the spectrum of peracetylated ribopyranose is used as an example to illustrate this and to trace and discuss the origin of the phenomena observed.