𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of Imidazole and Hydrocyanic Acid Derivatives on the ‘Possible Prebiotic’ polyphosphate induced peptide synthesis in aqueous solution

✍ Scribed by Joseph Rabinowitz; Aioub Hampai

Publisher
John Wiley and Sons
Year
1978
Tongue
German
Weight
362 KB
Volume
61
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Glycine in aqueous solutions of trimetaphosphate or linear polyphosphate at pH adjusted to 8.1‐9.0, is condensed at room temperature to diglycine and very small amounts of triglycine. The addition of imidazole increases the yield of triglycine by a factor of almost 10; supplementary addition of magnesium ion does not increase this effect. On the contrary to what has been observed at pH 11.5‐12.0, the addition of sodium cyanide or cyanamide at pH 8.1‐9.0 diminishes strongly the yield of triglycine and to a lesser degree that of diglycine. The prebiotic significance of the condensation of amino acids in aqueous solutions of polyphosphates in the presence of imidazole is discussed.

📜 SIMILAR VOLUMES

Synthesis of phosphorous acid and its de
Synthesis of phosphorous acid and its derivatives based on the reaction of elemental phosphorus (P4) and aqueous solution of choline in the presence of the hydroxides of earth alkali metals
✍ Elena V. Platova; Elvira S. Batyeva; Lidiya I. Kursheva; Oleg G. Sinyashin 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 78 KB 👁 1 views

## Abstract A nonchloric method for the synthesis of phosphorous acid and barium and calcium phosphites is proposed, involving the reaction of elemental phosphorus (P~4~) with aqueous barium and calcium hydroxides in the presence of quaternary ammonium base (choline). Conditions for the preparation