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Influence of ibuprofen on drug-metabolizing enzymes in rat liver in vivo and in vitro

✍ Scribed by Claus Reinicke; Wolfgang Klinger


Book ID
115772691
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
266 KB
Volume
24
Category
Article
ISSN
0006-2952

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Postmortem changes in the drug-metabolizing enzymes in rat liver microsome were studied. Parameters investigated were: microsomal protein, NADPH-cytochrome P-450 reductase activity, NADH-cytochrome b5 reductase activity, cytochrome b5 content, cytochrome P-450 content, aminopyrine N-demethylase acti