The magnetic field dependence of the water-proton spin-lattice relaxation rate (1/T(1)) in tissues results from magnetic coupling to the protons of the rotationally immobilized components of the tissue. As a consequence, the magnetic field dependence of the water-proton (1/T(1)) is a scaled report o
Influence of glycogen on water proton relaxation times
β Scribed by J. C. Gore; M. S. Brown; C. T. Mizumoto; I. M. Armitage
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 181 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0740-3194
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β¦ Synopsis
NMR imaging provides excellent soft tissue contrast which arises primarily because of the heterogeneous distribution of tissue relaxation times T I and T 2 . As a result, NMR has the potential for in vivo tissue characterization based on measurements of these relaxation properties, but there are still major deficiencies in our understanding of detailed relaxation mechanisms in heterogeneous tissues. This is the case both for normal tissues and for pathological alterations that occur during the course of disease. The specificity of such changes remains to be established and is partly dependent on the nature of any normal variations that occur in any tissue. In efforts to improve our understanding of tissue water relaxation behavior, several workers have measured relaxation times and high-resolution spectra of tissues and have correlated these with simultaneous determinations of tissue protein, lipid, metal content, and other tissue
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## Abstract ## Purpose To provide a straightforward method for metabolite quantitation in the brain. Tissue water concentration can be determined in a voxel by measuring T~1~ and it may provide an internal reference for the calculation of the metabolite concentrations. ## Materials and Methods W
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