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Influence of gender and age of onset on the outcome in children with systemic lupus erythematosus

✍ Scribed by Sulaiman M. Al-Mayouf; Abdullah Al Sonbul

Publisher
Springer
Year
2008
Tongue
English
Weight
79 KB
Volume
27
Category
Article
ISSN
0770-3198

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## Abstract ## Objective Accumulation of apoptotic cells may lead to the development of systemic lupus erythematosus (SLE) through a breakdown in immune tolerance. Altered neutrophil apoptosis may contribute to nuclear autoantigen exposure, ultimately leading to autoantibody generation. This study