Influence of Functional Groups on the Site-Selective Dissociation of Adenine upon Low-Energy Electron Attachment
✍ Scribed by Stephan Denifl; Philipp Sulzer; Dieter Huber; Fabio Zappa; Michael Probst; Tilmann D. Märk; Paul Scheier; Natcha Injan; Jumras Limtrakul; Robert Abouaf; Henri Dunet
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 176 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0044-8249
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✦ Synopsis
Recently an increasing number of dissociative electron attachment (DEA) studies have been performed with isolated biomolecules in the gas phase. [1] Interest in these molecules rose from the discovery that electrons with energies below 15 eV can induce substantial yields of single-and doublestrand breaks in plasmid DNA. [2] This damage of DNA was attributed to the fast decay of transient negative resonances localized on the DNA base constituents. [1] For nucleobases the most abundant anion formed is the closed-shell dehydrogenated molecular anion [Eq. ( 1)]. Here, M À * is the transient