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Influence of eicosanoids on serotonin release in the rat brain: inhibition by prostaglandins E1and E2

✍ Scribed by Eberhard Schlicker; Klaus Fink; Manfred Göthert

Book ID
112275026
Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
733 KB
Volume
335
Category
Article
ISSN
0028-1298

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Prostaglandin E1-(PGE1-) induced inhibition of pentylenetetrazol (PTZ) convulsions in rats were significantly antagonized after pretreatment with drugs known to reduce brain serotonin activity, but not by pharmacological agents that decrease brain catecholamine activity. PGF2alpha also significantly