Influence of P-glycoprotein on the trans
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P. Pรกvek; Z. Fendrich; F. ลกtaud; J. Malรกkova; H. Brozmanovรก; M. Lรกznรcek; V. Sem
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Article
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2001
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John Wiley and Sons
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English
โ 243 KB
The transfer kinetics of cyclosporine across the dually perfused rat placenta in the maternal to fetal direction and a possible involvement of P-glycoprotein were investigated. The transplacental clearance of cyclosporine in the maternoยฑfetal direction was found to be dependent on the maternal inยฏow